A leading authority on Supreme Court practice and nationally recognized expert on criminal procedure, Jeffrey L. Fisher's work at the law school revolves around handling cases in the U.S. Supreme Court. He has argued 23 cases in the Court, on issues ranging from criminal justice to maritime law to telecommunications law.

His successes include the landmark cases of Crawford v. Washington and Melendez-Diaz v. Massachusetts, in which he persuaded the Court to adopt a new approach to the Constitution's Confrontation Clause; Riley v. California, in which the Court for the first time applied the Fourth Amendment's protections against unreasonable searches to digital information on smart phones and other computers; Blakely v. Washington, in which the Court held that the Sixth Amendment right to a jury trial applies to sentencing guidelines; and Kennedy v. Louisiana, in which the Court held that the Eighth Amendment prohibits states from imposing capital punishment for crimes against individuals that do not result in death. In 2006, The National Law Journal named Professor Fisher one of the 100 most influential lawyers in America—the youngest person on the list.