Joseph R. Biden III, 46, the former attorney general of Delaware and the eldest son of Vice President Joe Biden, died on Saturday May 30, 2015 after losing his battle with brain cancer in Washington, D.C.

In this photo, Biden, known as Beau, waves to the audience on the final day of the Democratic National Convention in the Time Warner Cable Arena in Charlotte, North Carolina, Sept. 6, 2012,

a minor stroke in 2010 that kept him out of office for several weeks. In 2013 he was treated at the University of Texas MD Anderson Center Center in Houston after becoming weak and disoriented on a family vacation, undergoing what a member of his medical team later described as surgery to remove a "small lesion" in his brain.

On Sunday after Biden's death, the vice president's office confirmed Beau Biden was diagnosed with brain cancer in August 2013 and underwent the surgery at MD Anderson, which was followed by a normal course of treatment of radiation and chemotherapy. His doctor gave him a clean bill of health in November 2013.

After completing two terms as attorney general in January 2015, Biden said he wanted to run for governor in 2016 and in recent weeks his law firm said he had expanded his role.

But according to the vice president's office, Beau Biden suffered a recurrence in the spring of this year and immediately sought aggressive treatment.